Phlo Clinic weight loss service pack image
Phlo Clinic for weight loss success
Lose up to 20% of your bodyweight in under 18 months
Weight loss service
GLP-1/GIP

Weight loss injections & tablets

Buy safe & supported weight loss treatments and increase your chance of sustained weight loss. Achieve up to a 20% reduction in bodyweight*. Start the journey to a healthier (and lighter) you.

Trustpilot Phlo is rated excellent 4.8 out of 5
Prices from

£89

Get started

Manufacturer-sourced medications

Free Tracked 24 delivery

Clinical experts & monthly check-ins

No hidden fees (pay-as-you-go)

Weight loss treatment options

Buy our ground-breaking weight loss injections & pills that have been scientifically proven to boost your weight loss
when used in combination with lifestyle & dietary adjustments. We offer a price match scheme on GLP-1 medication to help keep your costs down whilst still getting access to our treatments and clinical support.

How weight loss injections work

Weight loss injections work by mimicking hormones your body naturally produces after eating. These hormones signal to your brain that you are full, slow the rate at which your stomach empties, and help reduce appetite between meals. The result is that you eat less, feel satisfied sooner, and experience fewer food cravings throughout the day.

The medications Phlo Clinic prescribes target one or two of these hormone pathways:

  • GLP-1 (glucagon-like peptide-1): A hormone released in the gut after eating. It suppresses appetite, slows gastric emptying, and helps regulate blood glucose levels. Wegovy (semaglutide) mimics GLP-1.

  • GIP (glucose-dependent insulinotropic polypeptide): A second gut hormone that enhances the effects of GLP-1, improves how the body processes fat and sugar, and is thought to increase the overall weight loss effect. Mounjaro (tirzepatide) mimics both GLP-1 and GIP, making it a dual agonist.

  • Lipase inhibition: Orlistat works differently. Rather than affecting appetite hormones, it blocks the enzymes that break down dietary fat in the gut, meaning your body absorbs roughly a third less fat from each meal.

All three mechanisms are supported by extensive clinical trial data and are approved for use in the UK by the Medicines and Healthcare products Regulatory Agency (MHRA).

Phlo Clinic teal and white packaging boxes and a smartphone screen showing a dietitian profile with meal plans and snack guide.

Why choose Phlo Clinic
for weight loss treatment?

What's included with your order

FREE Royal Mail Tracked 24 delivery (temperature-controlled)

Everything you need to get started with your first delivery, including sharps bin, welcome booklet and guide

Access to recipes, webinars, nutrition guide – all from our Obesity Specialist Dietitian

Graphic showing weight loss on mounjaro vs wegovy
Up to 20.7% weight loss

Thinking about switching from Mounjaro to Wegovy?

Transitioning from Mounjaro to Wegovy can be safe and manageable with the right guidance. Our expert clinical team and pharmacists are here to support you every step of the way.

From £89

More about switching to Wegovy

Weight loss medication comparison

Mounjaro

Wegovy
Orlistat
Ozempic
(not licensed
for weight loss)

Active ingredient

How to take

How often to take it

Supply provided

Class of drug

What does it do?

Initial price

Prescription only?

Available in the UK?

Supplied by
Phlo Clinic?

Delivery costs

Tirzepatide

Kwikpen injection

Once a week

4-week supply

GLP-1, GIP

Curb appetite and reduce cravings

£149

Yes

Yes

Yes

Free delivery

Semaglutide

FlexTouch injection

Once a week

4-week supply

GLP-1

Curb appetite and reduce cravings

£89

Yes

Yes

Yes

Free delivery

Orlistat

Oral capsule

capsule, 3x a day

4-week supply

Stop absorbing as much fat in foods and reduce caloric intake

£89

Yes

Yes

Yes

Free delivery

Semaglutide

Weekly injection

Once a week

4-week supply

GLP-1

Helps the body make more insulin and lowers blood sugar levels

N/A

Yes

Yes

No

N/A

How does each weight loss treatment compare?

Navigating the landscape of weight loss medication can be complex. Phlo Clinic offers three primary, manufacturer-sourced treatments: Wegovy, Mounjaro, and Orlistat. Each operates through a different mechanism to support your goals.

We provide a price match scheme on GLP-1 medications to ensure accessibility. This allows you to benefit from competitive pricing while retaining access to our fully managed clinical service, monthly check-ins, and free tracked delivery.

Wegovy (Semaglutide)

Wegovy is a leading GLP-1 receptor agonist that has transformed medical weight management. The active ingredient, semaglutide, mimics a natural hormone that targets areas of the brain involved in regulating appetite and food intake.

Key facts:

  • Format:

    Weekly self-injection via the FlexTouch pen

  • Efficacy:

    Clinical trials show up to 20.7% weight loss

  • Dosage:

    Titrated from 0.25mg to 2.4mg to manage tolerance

This medication is particularly effective for those who struggle with intense cravings. By slowing gastric emptying, it helps you feel fuller for longer, significantly reducing daily calorie intake without the sensation of deprivation.

Mounjaro (Tirzepatide)

Mounjaro represents the next generation of weight management treatments. It’s unique because it acts as a dual agonist, targeting both GLP-1 and GIP receptors. This dual action enhances the body's natural ability to regulate blood sugar levels and fat metabolism while suppressing appetite.

Key facts:

  • Format:

    Weekly self-injection via the KwikPen

  • Efficacy:

    Studies demonstrate up to 20% weight loss

  • Dosage:

    Ranges from 2.5mg to 15mg

Because it targets two hormonal pathways simultaneously, Mounjaro is often considered a potent option for patients who require significant weight reduction. Like Wegovy, it is a prescription-only medicine that requires clinical oversight.

Orlistat

For patients seeking a non-injectable alternative, Orlistat offers a different approach. Instead of altering hormones or brain chemistry, Orlistat works in the digestive system. It acts as a lipase inhibitor, preventing your body from breaking down and absorbing approximately one-third of the fat from the food you eat.

Key facts:

  • Format:

    Oral capsule taken three times daily with meals

  • Efficacy:

    Can help reduce overall body fat by 5%

  • Dosage:

    Blocks dietary fat absorption

Orlistat is ideal for individuals who prefer oral medication over needles and are committed to a lower-fat diet. The unabsorbed fat is naturally eliminated from the body, making dietary compliance essential for comfort and effectiveness.

Coming soon later this year, will be
Wegovy available in tablet form

Lose up to 20% of your bodyweight in under 18 months

Weight loss calculator

kgs
lbs
Select your current weight:
144
kgs
Weight you could lose:
144
kgs

*This calculator is only an example for illustrative purposes and the results are not guaranteed. Every weight loss experience is unique. This example is based on research showing weight loss of up to 20% over a 72-week period

With you at every high and low

How much weight can you lose on weight loss medication?

Studies have shown combining weight loss medications with diet and exercise can have a greater reduction in bodyweight, when monitored over the same time period.

0 - 3 months

Kickstart your journey

Start feeling less hungry

Less food noise

Noticeable weight loss progress and more energy

It can take up to 8 weeks to start feeling the effects of your medication, but it will start working in your body after the first week.

3 – 6 months

Positive changes

A noticeable reduction in bodyweight

Be more active and making healthier food choices

With Phlo Clinic, gain education on relationship with food

As your dosage increases you should see changes in your weight and your lifestyle.

6 – 12 months

Sustained weight loss

Continued weight loss

Improvements in measurable health metrics e.g. reduced blood pressure, improved cholesterol or blood glucose control

Formulate a personal comprehensive plan for long-term weight control

This is a period where you’ll see sustained weight loss and be in a consistent weight management rhythm.

With you at every high and low

What can you expect

Studies have shown combining weight loss medications with diet and exercise can have a greater reduction in bodyweight, when monitored over the same time period.

0 - 3 months

Kickstart your journey

Start feeling less hungry

Notice increased energy levels

Redefine your relationship with food

Read more
3 – 6 months

Positive changes

See a reduction in your bodyweight

Feel more in control of your appetite

Be more active and making healthier food choices

Read more
6 – 12 months

Sustained weight loss

Continued weight loss and more energy

Improvements to your metabolic health and any weight-related health conditions

Define a long-term weight management plan

Read more
Weight loss medication Clinical study results
Mounjaro People lost up to 22.5% of their starting weight on the 15mg maintenance dose after 72 weeks
Wegovy People lost an average 21% of their starting weight after 72 weeks on the 7.2mg maximumm dose.
Orlistat Found to help 37% of people lost 5% or more of their starting weight after 12 weeks.

Real customer weight loss stories

Share in the weight loss experiences of Phlo Clinic patients just like you and why they trust us to help achieve their goals.

Your safe & supported weight loss journey

Our approach to weight loss treatments is based on three core factors - designed with you and your long-term health as our priority.

Suitability

Assessing your current and past medical 
history to make sure it’s safe for you.

Success

Factoring in your weight loss
goals to determine your chance of a successful outcome.

Safety

Monthly monitoring via our clinical team, with your health & wellbeing at the centre.

Who is eligible for weight loss injections

You are aged between 18 and 85

You have a BMI above 30 or have a BMI above 27 and a weight-related accompanying condition

(e.g. high blood pressure or cholesterol amongst others)

If you’re already on GLP-1 medication and switch to Phlo Clinic, we require a BMI of above 23 with supporting evidence

Supply photographic evidence to verify your consultation.

Meet all other clinical criteria subject to your medical history and GP records.

During the consultation stage we’ll ask you for more specific information to help you find the right treatment.

BMI criteria for
weight loss injections

Prescription weight loss treatments are not suitable for everyone. Eligibility is assessed on the basis of your BMI and any weight-related health conditions, alongside a review of your full medical history and current medications.

Treatment Minimum BMI
(no conditions)
Mimimum BMI
(with weight-related conditions)
Wegovy 30 or above 20 or above
Mounjaro 30 or above 20 or above
Orlistat 30 or above 20 or above

Weight-related conditions that may lower the BMI threshold include high blood pressure, type 2 diabetes, high cholesterol, obstructive sleep apnoea, and cardiovascular disease.

Other eligibility
requirements

In addition to the BMI criteria laid out above, to be considered for any prescription weight loss treatment through Phlo Clinic, you must also:

  • Be aged 18 or over

  • Not be pregnant or breastfeeding

  • Have no known allergy to the active ingredients

  • Not have certain contraindicated medical conditions (assessed during your consultation)

You should also disclose to your prescribing pharmacist if you have a history of any other medical conditions, such as pancreatitis or eating disorders.

Weight loss advice
Got weight loss questions?

Get weight loss answers.

Find out what you need to know about how our weight loss service works. From ordering to payments and everything in between - read the latest from our specialists.

Visit advice hub
Here to help

Is it time to order your next treatment?

Tap the re-order button to access your Phlo Clinic account and complete your re-order consultation.

Frequently asked questions

Will I be eligible for weight loss treatment?
What are injectable weight loss medications?
How do weight loss injections work?
What weight loss medication do you offer?
Can I take weight loss treatments alongside other medications?
Are Mounjaro and Wegovy safe?
Are there side effects from taking the weight loss medication?
How to administer your weight loss injection
How do I dispose of my sharps bin?
How much do weight loss treatments cost?
How much weight can you lose?
How do I re-order my next dose?
What do weight loss injections contain?
Who checks my consultation?
What evidence do I need to provide if I’m transferring from another GLP-1 provider?

Side effects of weight loss medication

Like all prescription medications, weight loss treatments can cause side effects. Most are mild to moderate and tend to improve as your body adjusts to the medication, particularly during the dose escalation phase. Serious side effects are uncommon but should be reported to your Phlo Clinic clinical team immediately.

Common side effects by treatment

Wegovy (semaglutide):

  • Nausea

  • Vomiting

  • Diarrhoea

  • Constipation

  • Headache

  • Fatigue

  • Abdominal pain or discomfort

Mounjaro (tirzepatide):

  • Nausea

  • Vomiting

  • Diarrhoea

  • Constipation

  • Abdominal pain

  • Reduced appetite (beyond the intended effect)

  • Injection site reactions

Orlistat:

  • Oily or fatty stools

  • Increased or urgent need to use the toilet

  • Oily discharge

  • Flatulence with discharge

  • Abdominal discomfort

  • Headache

The most common side effects of GLP-1 injections (nausea, vomiting) are typically dose-dependent and most pronounced during the escalation period. You can help manage them by:

  • Eating smaller, more frequent meals

  • Avoiding high-fat, spicy, or greasy foods, particularly in the first weeks of treatment

  • Staying well hydrated

  • Resting adequately

For orlistat, the gastrointestinal side effects are directly related to fat intake. Keeping dietary fat below 30% of total calories per meal significantly reduces their occurrence.

1

Quick & easy questionnaire

To make sure you can safely take your preferred treatment, complete our questionnaire which takes approx 3 mins.

2

We review

Our prescribing pharmacists review and individually assess your treatment suitability using their extensive knowledge and clinical experience.

3

We deliver

Once approved and dispensed, we’ll securely deliver your treatment anywhere you need using our free Royal Mail Tracked 24 option.

1

Quick & easy questionnaire

To make sure you can safely take your preferred treatment, complete our questionnaire which takes approx 3 mins.

2

We review

Our prescribing pharmacists review and individually assess your treatment suitability using their extensive knowledge and clinical experience.

3

We deliver

Once approved and dispensed, we’ll securely deliver your treatment anywhere you need using our free Royal Mail Tracked 24 option.

Weight loss
GLP-1/GIP
Tirzepatide

The alternative to non-reversible weight loss surgeries

Phlo Clinic
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Reviewed by:
Dennis Ouko
|
2205052
|
Superintendent Pharmacist
Last reviewed:
April 2, 2025
Next review:
November 30, 2026
Weight loss service
|
Price from
£89