Mounjaro Side Effects: Nausea & Vomiting

Last reviewed
March 11, 2025
Reviewed by
Jaanki Kotecha
Next review
March 11, 2026
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If you’ve recently started Mounjaro and are experiencing nausea or vomiting, you’re not alone. These are common side effects, especially in the early stages of treatment or when increasing your dose. While they can be uncomfortable, there are ways to manage them effectively.

In this guide, we’ll explain why Mounjaro can cause nausea and vomiting and share practical tips to help ease these symptoms. If you’d like a full overview of all potential side effects, check out our Mounjaro side effects guide.

Does Mounjaro cause nausea?

Nausea is a common side effect of Mounjaro. In research trials, 1 in 5 Mounjaro users (20%) reportedly experienced nausea. Tirzepatide (the active drug in Mounjaro) slows down how quickly the stomach empties. This can lead to feelings of fullness and discomfort, especially when starting treatment or increasing doses.

Does Mounjaro cause vomiting?

Vomiting is a reported side effect of Mounjaro, although it’s less common than nausea, with less than 1 in 10 (approximately 9%) of users reporting this side effect. It is typically associated with higher doses or rapid dose escalation and can accompany nausea in some cases.

 

What can I do to help with nausea and vomiting during Mounjaro treatment?

Some dietary strategies can help reduce nausea and vomiting and are worth trying first.

  • Eat small, frequent meals: Instead of three large meals, try having smaller portions more often throughout the day, as this will help keep blood glucose levels stable. This could include breakfast, a mid-morning snack, lunch, a mid-afternoon snack, an evening meal, and a light snack before bed.
  • Stay hydrated: Sip on clear fluids like water or herbal tea, and avoid or limit sugary drinks, caffeine, and alcohol. Staying hydrated supports digestion and helps prevent dehydration caused by vomiting. If you experience prolonged vomiting, an oral rehydration solution may be necessary – please speak to our Pharmacists at Phlo for advice.
  • Choose bland foods: Plain options like crackers, toast, rice, or bananas are easier to digest and gentle on the stomach. These foods are low in fat and fibre, making them easier to tolerate.  
  • Avoid strong smells and flavours: When feeling unwell, it’s helpful to limit hot, spicy, or high-fat foods, as these can trigger or worsen nausea. They may be harder to digest and may increase stomach irritation. Choosing milder, lower-fat foods can help reduce the risk of worsening symptoms.
  • Incorporate ginger: Ginger may help with nausea relief. Try adding small amounts of fresh ginger to your meals or enjoy a soothing cup of ginger tea. It’s known to aid digestion and has anti-inflammatory properties that can help calm an irritated stomach.  
  • Eat slowly: Take your time while eating, as this helps promote better digestion and reduces the risk of bloating, discomfort, or indigestion. Avoid lying down immediately after meals, as this can cause stomach acid to flow back into the oesophagus, leading to heartburn or reflux that can worsen nausea.

If you’re still struggling with nausea or vomiting after trying these strategies, please speak to our team of Pharmacists at Phlo Clinic, who can assist you further.

Ready to start your Mounjaro journey?

Start a free consultation for the Mounjaro KwikPen today!

Created & reviewed by:
Jaanki Kotecha
|
Pharmacist Independent Prescriber
Last reviewed:
March 11, 2025
Next review:
March 11, 2026
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