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If you've recently started Mounjaro (Tirzepatide) and find yourself reaching for an extra jumper more often than usual, you're not alone.
Feeling unusually cold is a side effect some people experience while taking Mounjaro. While it might not be widely discussed, it can feel unsettling if you’re not expecting it.
Let’s break it down and explore what might be going on, and what you can do to feel more comfortable.
Can Mounjaro Make You Feel Cold?
Yes, it can. Although not officially listed as a common side effect, many people report feeling cold on than usual, particularly during the early weeks of treatment or during periods of rapid weight loss. It can feel like a persistent chill, even when everyone else around you seems perfectly warm.
How Common Is Feeling Cold?
There aren’t specific statistics for this side effect, as "feeling cold" isn’t routinely measured in clinical trials. However, it’s a well-noted experience among users, particularly on forums and support groups. It’s not guaranteed to happen to everyone, but it’s common enough to be worth mentioning.
Why Might Mounjaro Cause Cold Sensitivity?
While there’s no single explanation, several factors may contribute:
- Changes in Metabolism: Mounjaro helps improve insulin sensitivity and slows digestion. These changes can affect your metabolic rate and how your body manages temperature.
- Reduced Calorie Intake and Digestion: Mounjaro often leads to a natural reduction in appetite. Eating fewer calories can mean your body has less energy available for generating heat.
- Weight Loss and Reduced Insulation: As you lose weight, you may also lose some of your body’s natural insulation. This can make you feel colder, especially in cooler environments or during periods of inactivity.
How to Manage Feeling Cold on Mounjaro
Here are some practical tips to help you stay warm and comfortable:
- Layer Up: wearing layers is a simple but effective way to regulate your body temperature throughout the day. Consider thermal socks, base layers, or even fingerless gloves indoors if needed.
- Stay Well Hydrated: drinking enough water supports healthy circulation and temperature control.
- Keep Moving: light exercise like walking or stretching can boost circulation and help warm you up from the inside out.
- Eat Balanced Meals Regularly: skipping meals or undereating can worsen cold sensitivity. Aim for regular, balanced meals with a good mix of carbohydrates, protein and healthy fats.
- Eat Warm Meals: eating warm meals, such as soups, stews or porridge, can help raise your body temperature and make you feel more comfortable if you're feeling the cold.
- Check Your Iron and Thyroid Levels: low iron levels (anaemia) or an underactive thyroid (hypothyroidism) can increase cold sensitivity. If you’re concerned, speak to your GP.
- Talk to Your Prescriber About Your Dose: if the cold sensitivity is affecting your quality of life, reach out to our Patient Care team who can put you in touch with one of our prescribers. Adjusting your dose or slowing the escalation might help.
When Should I Seek Medical Advice?
While feeling a bit chilly now and then isn’t usually a cause for concern, you should contact your healthcare provider if:
- You constantly feel cold, regardless of the environment
- Your hands and feet are regularly numb or tingling
- You’re also feeling weak, tired, or dizzy
- You’re experiencing very rapid weight loss
- You suspect an issue with your thyroid or iron levels
Your comfort and safety come first so don’t hesitate to get in touch if something feels off.
Feeling cold on Mounjaro can be unexpected, but it’s not uncommon and it’s usually manageable. With the right strategies and support, you can stay warm and continue progressing towards your health goals. If you’re unsure about anything, speak to our support team - we’re here to help.
