Some people taking Wegovy (Semaglutide) notice they feel more tired than usual. While fatigue hasn’t been reported as a major side effect in clinical trials, it can occur, particularly during the first few weeks as your body adjusts to the medication and changes in your diet.

If you’ve experienced lower energy levels since starting Wegovy, you’re not imagining it. Fatigue may result from several factors, including reduced calorie intake, fluctuations in blood glucose, changes in digestion, or mild dehydration. The good news? There are simple, practical strategies to help support your energy while staying on track with your weight management goals.

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Why can Wegovy make you feel tired

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Tiredness while taking Wegovy can result from:

• Eating fewer calories than your body is used to
• Changes in digestion or slower stomach emptying
• Fluctuations in blood glucose levels
• Mild dehydration

Understanding these factors can help you take steps to reduce fatigue and feel more energised throughout the day.

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Strategies to combat fatigue from Wegovy

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1. Establish a calming bedtime routine

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Small habits can make a big difference. Consider switching off screens an hour before bed, keeping your room cool and dark, and winding down with a book or a warm shower.

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2. Prioritise quality sleep

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Getting 7-9 hours of sleep each night is essential, especially while your body is adjusting. Maintaining a consistent sleep routine - going to bed and waking up at roughly the same times every day - can help regulate your internal clock and improve sleep quality.

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3. Eat balanced, nutrient-rich meals

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Even if your appetite is reduced, your body still needs fuel. Focus on whole foods, lean proteins, and slow-release carbohydrates. Avoid skipping meals or relying on ultra-processed foods, which can lead to energy dips.

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4. Get morning light exposure

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Natural light in the morning helps regulate your circadian rhythm and can support energy levels throughout the day. A short walk outside or sitting near a bright window is a simple way to do this.

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5. Stay hydrated

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Even mild dehydration can cause fatigue. Aim to drink around 2-3 litres of fluids daily and keep a water bottle handy to help you reach your goal.

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6. Limit caffeine

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Caffeine can disrupt sleep, particularly if consumed later in the day. To help improve your rest and prevent feeling more tired the next day, try to avoid caffeine after 2pm.

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7. Move gently throughout the day

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Light activity, such as walking, stretching, or yoga, can boost energy levels and improve sleep. Start slowly and listen to your body, pacing yourself to avoid overexertion.

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Key takeaway for Wegovy fatigue

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Feeling more tired than usual on Wegovy is something some people experience, particularly in the early weeks. However, prioritising rest, eating balanced meals, staying hydrated, and finding a daily rhythm that works for you can all help improve energy levels.

Pay attention to how your body responds. If fatigue persists or worsens, speak with your healthcare provider to rule out other causes and ensure your treatment is on track.

Remember, managing your energy is an important part of overall wellbeing - it’s not just about your weight.