If you’re taking Mounjaro, you may be wondering whether it’s safe to drink alcohol while on this medication. While there are no known direct interactions between Mounjaro and alcohol, there are a few important things to keep in mind if you choose to drink.
Potential risks when drinking alcohol on Mounjaro
- Increased risk of gastrointestinal issues: Mounjaro can cause gastrointestinal side effects such as nausea, vomiting, and indigestion. Because Mounjaro slows gastric emptying significantly, alcohol may be absorbed more unpredictably than usual, and patients may feel its effects more strongly than expected. Alcohol is also a gastric irritant, and the combination can worsen nausea beyond what either would cause alone. This is especially relevant when you’re still adjusting to the medication.
- Dehydration and energy levels: Alcohol can contribute to dehydration, which may intensify side effects such as dizziness or fatigue. Staying well-hydrated and limiting alcohol intake can help reduce this risk.
- Impact on calorie intake: Many alcoholic drinks are high in calories. One unit of alcohol contains around 60kcal, roughly the same as a bourbon biscuit. Alcohol may also influence food choices both during and after drinking, often leading to higher-calorie, lower-nutrient options that can impact weight management.
- Blood glucose control: Alcohol affects blood glucose in a nuanced way. Sugary drinks such as cocktails, liqueurs, and full-sugar mixers can raise blood glucose, but alcohol itself tends to lower blood glucose levels by inhibiting the liver’s ability to release stored glucose. This means drinking, particularly on an empty stomach or in larger amounts, can increase the risk of low blood glucose. It’s important to be mindful of this, particularly if you have type 2 diabetes.
- Risk of pancreatitis: Mounjaro carries a known risk of pancreatitis, and alcohol is an independent risk factor for the same condition. Using both together may increase this risk. If you experience sudden, severe abdominal pain, particularly pain that radiates to the back, seek medical attention promptly. Do not take your next dose of Mounjaro until you have been assessed by a healthcare professional.
How to manage your alcohol tolerance while on Mounjaro
If you choose to drink alcohol while taking Mounjaro, it’s important to do so mindfully. While there are no specific drinking guidelines for Mounjaro, the UK Chief Medical Officers recommend no more than 14 units of alcohol per week to keep health risks from alcohol low. If you regularly drink up to 14 units a week, it should be spread across three or more days, with several drink-free days and no binge drinking. One unit equals 10ml of pure alcohol. It’s also important to remember that the risk of developing health problems such as mouth, throat and breast cancer increases the more you drink on a regular basis.
Here are some practical tips:
Don’t drink on an empty stomach:
Eating beforehand can help prevent drops in blood glucose. Choose meals with complex carbohydrates, protein and healthy fats to support more stable levels.
Choose lower-sugar drinks:
Dry wine, spirits like gin or vodka, or light beer are generally better options than sugary cocktails or full-sugar mixers.
Be mindful of portion sizes and frequency:
Keep track of how much you're drinking and how often throughout the week and be aware that home measures are often larger than those served at bars or restaurants.
While alcohol isn’t explicitly prohibited with Mounjaro, it’s best to proceed with caution. Many people find that their desire to drink decreases while on the medication.
By drinking in moderation, making informed choices and monitoring your blood glucose for those it concerns, it’s possible to enjoy alcohol safely while managing potential risks. Always consult your healthcare provider if you have any concerns or need individualised advice.
References
1. Eli Lilly and Company. Mounjaro (tirzepatide) Summary of Product Characteristics. European Medicines Agency; 2023. Available at: https://www.ema.europa.eu/en/medicines/human/EPAR/mounjaro
2. UK Chief Medical Officers. UK Chief Medical Officers’ Low Risk Drinking Guidelines. Department of Health; 2016. Available at: https://www.gov.uk/government/publications/alcohol-consumption-advice-on-low-risk-drinking
