Fasting and GLP-1 Medication
Fasting for religious reasons can present unique challenges for individuals taking GLP-1 medications. This post will explore how to continue using GLP-1 medications safely during fasting, potential side effects, and tips for managing them effectively.
Medication Use During Fasting
If you're taking an injectable GLP-1 medication, we generally recommend taking it on the same day and time each week. However, when you're fasting, you may need to be flexible and adjust the time you take it. During Ramadan, it’s ideal to take the GLP-1 medication with the last meal (sometimes called Suhoor) before beginning the fast, this adjustment may reduce gastrointestinal discomfort.
Reducing Your Dose
Whilst fasting, it may be difficult to maintain a balanced diet and the chances of developing low blood glucose (hypoglycaemia) can increase whilst taking GLP-1 medication. One of the ways you may reduce this risk is by lowering your dose to the next lowest dose. If you’d like to consider this, please discuss this with a member of our prescribing team who will be able to assist you further.
Common Side Effects During Fasting
These include:
- Headaches: These are often linked to dehydration or a reduction in usual caffeine intake. To alleviate headaches, aim to drink 2–3 litres of fluids during your eating window. Good options include water, tea, coffee, low-fat milk, or soya milk (choose unsweetened varieties). Herbal teas or infused water can also be refreshing alternatives. Fruits, with their high-water content, are another great way to support hydration while also providing essential nutrients.
- Heartburn & Indigestion: Heartburn may occur during fasting, as the smell and sight of food can increase gastric secretions. Both heartburn and indigestion can result from consuming spicy or high-fat foods, overeating, or eating too quickly. To manage these issues, avoid meals and snacks high in fat. Keep portion sizes moderate and prepare food using low-fat methods such as air frying, grilling, or roasting. Trimming visible fat from meat and removing skin before cooking can further reduce fat content and help prevent heartburn. Choose low-fat dairy or fortified plant-based alternatives as healthier choices.
- Constipation: This is a common issue during fasting, often caused by changes in diet, meal timing, and limited fluid intake throughout the day. It is also a well-known side effect of GLP-1 medications. To help alleviate constipation, aim to consume 30g of fibre and stay hydrated. Incorporating light physical activity, such as walking or yoga, can also help stimulate bowel movements.
- Changes in Weight: Weight loss is common during fasting due to reduced calorie intake, but weight gain can occur if food choices during the eating window are more calorie-dense, or if overeating occurs in anticipation of fasting. To manage this, try to establish regular mealtimes during your eating window. Planning meals in advance can help you make healthier choices. Meals should include all three macronutrients: carbohydrates, protein, and healthy fats. The T-plate method is a good guide.
Managing Side Effects of GLP-1 Medications
- Nausea and Vomiting: If you experience nausea or vomiting, try eating small, frequent meals during the eating window. Try to avoid spicy, fried, and strong-smelling foods. Choose mild, bland flavours instead. This can help reduce the likelihood of discomfort. Staying hydrated by sipping on fluids can also be beneficial.
- Diarrhoea: If you experience diarrhoea, try to avoid artificial sweeteners, as they can sometimes worsen symptoms. Diarrhoea can increase the risk of dehydration, so it’s especially important to stay hydrated. Aim to drink 2–3 litres of fluids during your eating window to maintain proper hydration.
- However, if side effects persist despite trying these strategies, please contact our Patient Care Team for further advice and support.
Consult with Phlo
If you have concerns about taking GLP-1 medication while fasting, it may be advisable to consider a temporary break during this time. You can discuss this option with our team of healthcare professionals at Phlo. Additionally, individuals with health complications are often exempt from fasting or allowed to modify their fasting practices, so this is something worth exploring.
For more information or to discuss any concerns, please reach out to our team at Phlo. We are happy to provide guidance and ensure your health is managed safely during fasting.
